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2,5-dimethylpyrazine

roasted pyrazine

Found in 97 ingredients across the CompKitchen flavor graph.

Look up another compound — search by name, CAS number, PubChem CID, or FEMA #.

2D Lewis structure of 2,5-dimethylpyrazine
2D Lewis Structure
Formula
C6H8N2
Molecular weight
108.14 g/mol
PubChem CID
31252 — full record on PubChem

Properties

Odor description
cocoa, roasted, nutty
Odor threshold — orthonasal, in clean water
1300 ppb 1 published value · see all 3 with sources
Volatility
high
CAS number
123-32-0
Retention index
916
Regulatory · United States

FEMA GRAS — Generally Recognized As Safe for flavoring use

? Partial match
FEMA number
3150
GRAS publication
GRAS 4
FEMA primary name
3-ETHYL-2,5-DIMETHYLPYRAZINE

Use-level matrix not extracted for this substance — check the source publication for current ppm guidance.

Source: FEMA GRAS publications 1-33.

How this molecule is described

Sources disagree about odour more often than they disagree about chemistry. Rather than show one answer, here is every description on file with how many ingredient records carry it.

Also filed as
2,5-dimethyl-pyrazine

Same molecule, unified here — previously counted and displayed as separate compounds.

Descriptions on file

Ordered by how many independent descriptor streams give each wording, then by how often it appears. The bar is still replication — one source copied onto many ingredients scores high there — so the two can disagree.

cocoa, roasted, nutty shown above Flavornet Cas, Flavornet Name, Flavordb Odor Column 3 sources agree
—
solvent, chemical FlavorDB 2.0, Flavordb Odor Column 2 sources agree
2
roasted, meaty, almond FlavorDB 2.0, Flavordb Odor Column 2 sources agree
1
cocoa, grass, medical, medicinal, medicine, roast beef, roasted nut, roasted nuts, woody FlavorDB 2.0
59
cocoa, roasted nut, roast beef, medicine, medicinal, roasted nuts, woody, grass, medical, roastednut, roastbeef FlavorDB 2.0
22
roasted peanutty FlavorDB 2.0
1

Bars are the share of ingredient records carrying each description. High agreement means the sources replicate each other — not necessarily that they are right.

Published thresholds

3 measured values from the literature. Grouped by what was actually measured — a threshold smelled in clean water, tasted in the mouth, or measured in a real food are three different quantities and are not pooled.

Orthonasal, in clean water

1300 ppb

The reference measurement — smelled in water. OAV is computed against this.

Threshold Matrix Source Paper
1300 ppb water_odor Leffingwell —

In a food matrix

14.4 ppb – 982 ppb

Measured in a real food, where the matrix shifts detection — not a clean-water value.

Threshold Matrix Source Paper
14.4 ppb water (food: coffee) Literature corpus —
982 ppb water (food: unknown) Literature corpus —

Only values we can attribute are listed. Where a compendium's licence does not permit public attribution its figures are omitted here, so every number on this page traces to a citable source.

Where you'd actually smell it

Odor Activity Value = measured concentration ÷ odor threshold (516.0 ppb, the engine's canonical value — see the 3 published values). OAV ≥ 1 = perceptible.

Food Concentration (ppb) OAV Source
flour 20000.0 38.8 ⚡ DOI
lard 17570.0 34.0 ⚡ PMID 31304252
sunflower seed 1300.0 2.52 PMID 31383910
tuna 16.0 0.03 PMID 33026027
bread 17.0 0.03 PMID 38840722
shrimp 15.0 0.03 DOI

Concentrations from PubMed Central Open Access papers (free literature corpus, MIT-style licensed). Copper = OAV ≥ 10 (strongly perceptible). Green = OAV ≥ 1 (perceptible).

Found in

Measured impact first, then profile share

Every ingredient known to contain 2,5-dimethylpyrazine. Ingredients with a measured concentration come first, ranked by odour activity; the rest follow by how large a share of that ingredient's profile this molecule is. The figure beside each is how many different compounds that ingredient has in total — not the concentration of 2,5-dimethylpyrazine in it. Full concentrations are in the OAV table above.

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