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3-methoxypyrazine

Key food odorant

Found in 1 ingredient across the CompKitchen flavor graph.

Look up another compound — search by name, CAS number, PubChem CID, or FEMA #.

Key food odorant (intermediary)

Dunkel et al. 2014

Identified in the meta-analysis of 227 food samples as one of 57 intermediary odorants — appears in 5–25% of foods.

Source: Angew. Chem. Int. Ed. 2014, 53, 7124–7143

Properties

Odor description
butter, pepper, coffee, roasted
Odor threshold — orthonasal, in clean water
5.0 ppb – 10.0 ppb median 5.0 ppb · 3 published values · see all 6 with sources
CAS number
25773-40-4
Regulatory · United States

FEMA GRAS — Generally Recognized As Safe for flavoring use

? Partial match
FEMA number
3132
GRAS publication
GRAS 4
FEMA primary name
2.iso-BUTYL-3-METHOXYPYRAZINE

Use-level matrix not extracted for this substance — check the source publication for current ppm guidance.

Source: FEMA GRAS publications 1-33.

How this molecule is described

Sources disagree about odour more often than they disagree about chemistry. Rather than show one answer, here is every description on file with how many ingredient records carry it.

Descriptions on file

Ordered by how many independent descriptor streams give each wording, then by how often it appears. The bar is still replication — one source copied onto many ingredients scores high there — so the two can disagree.

butter, pepper, coffee, roasted shown above FlavorDB 2.0
1
butter, pepper, coffee Flavordb Odor Column
—
butter Flavordb Odor Column
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butter, roasted, pepper, coffee Flavordb Odor Column
—

Bars are the share of ingredient records carrying each description. High agreement means the sources replicate each other — not necessarily that they are right.

Published thresholds

6 measured values from the literature. Grouped by what was actually measured — a threshold smelled in clean water, tasted in the mouth, or measured in a real food are three different quantities and are not pooled.

Orthonasal, in clean water

5.0 ppb – 10.0 ppb

The reference measurement — smelled in water. OAV is computed against this.

Threshold Matrix Source Paper
0.003 ppb SIDA water Rychlik 1998 · 2 studies —
Flagged: 1667× from the median of this group. Excluded from the range above pending re-check against the source publication — shown rather than hidden.
5.0 ppb water_odor Leffingwell —
10.0 ppb water_odor Leffingwell —

In a food matrix

0.004 ppb – 0.013 ppb

Measured in a real food, where the matrix shifts detection — not a clean-water value.

Threshold Matrix Source Paper
0.004 ppb water (food: reference standard (water)) Literature corpus —
0.013 ppb water (food: beef vegetable gravy) Literature corpus —
0.013 ppb water (food: pork vegetable gravy) Literature corpus —

Only values we can attribute are listed. Where a compendium's licence does not permit public attribution its figures are omitted here, so every number on this page traces to a citable source.

Where you'd actually smell it

Odor Activity Value = measured concentration ÷ odor threshold (0.013 ppb, the engine's canonical value — see the 6 published values). OAV ≥ 1 = perceptible.

Food Concentration (ppb) OAV Source
coffee 5000.0 384615 ⚡ Corpus paper
beef 1.0 76.9 ⚡ Corpus paper
cocoa 0.3 22.3 ⚡ Corpus paper

Concentrations from PubMed Central Open Access papers (free literature corpus, MIT-style licensed). Copper = OAV ≥ 10 (strongly perceptible). Green = OAV ≥ 1 (perceptible).

Found in

Measured impact first, then profile share

Every ingredient known to contain 3-methoxypyrazine. Ingredients with a measured concentration come first, ranked by odour activity; the rest follow by how large a share of that ingredient's profile this molecule is. The figure beside each is how many different compounds that ingredient has in total — not the concentration of 3-methoxypyrazine in it. Full concentrations are in the OAV table above.

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