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4-methylphenol

spicy phenol Key food odorant

Found in 98 ingredients across the CompKitchen flavor graph.

Look up another compound — search by name, CAS number, PubChem CID, or FEMA #.

2D Lewis structure of 4-methylphenol
2D Lewis Structure
Formula
C7H8O
Molecular weight
108.14 g/mol
PubChem CID
2879 — full record on PubChem

Key food odorant (intermediary)

Dunkel et al. 2014

Identified in the meta-analysis of 227 food samples as one of 57 intermediary odorants — appears in 5–25% of foods. Characteristic odor: phenolic, smoky, barnyard.

Source: Angew. Chem. Int. Ed. 2014, 53, 7124–7143

Properties

Odor description
phenolic, smoky, animal, medicinal
Odor threshold — orthonasal, in clean water
55.0 ppb 1 published value · see all 16 with sources
Volatility
high
CAS number
106-44-5
Retention index
1100
Regulatory · United States

FEMA GRAS — Generally Recognized As Safe for flavoring use

? Partial match
FEMA number
2671
GRAS publication
GRAS 3
FEMA primary name
2-METHOXY-4-METHYLPHENOL

Use-level matrix not extracted for this substance — check the source publication for current ppm guidance.

Source: FEMA GRAS publications 1-33.

How this molecule is described

Sources disagree about odour more often than they disagree about chemistry. Rather than show one answer, here is every description on file with how many ingredient records carry it.

Also filed as
4-methyl-phenol p-cresol

Same molecule, unified here — previously counted and displayed as separate compounds.

Descriptions on file

Ordered by how many independent descriptor streams give each wording, then by how often it appears. The bar is still replication — one source copied onto many ingredients scores high there — so the two can disagree.

medicine, phenol, smoke Flavornet Cas
—
woody, honey, caramel, butter, smoky FlavorDB 2.0, Flavordb Odor Column 2 sources agree
1
medicine, phenol, smoke, medicinal, phenolic, narcissus, animal, mimosa FlavorDB 2.0
57
butter, chemical, cooked FlavorDB 2.0
3
smoky FlavorDB 2.0
2
phenolic, animal-like FlavorDB 2.0
1

Bars are the share of ingredient records carrying each description. High agreement means the sources replicate each other — not necessarily that they are right.

Published thresholds

16 measured values from the literature. Grouped by what was actually measured — a threshold smelled in clean water, tasted in the mouth, or measured in a real food are three different quantities and are not pooled.

Orthonasal, in clean water

55.0 ppb

The reference measurement — smelled in water. OAV is computed against this.

Threshold Matrix Source Paper
55.0 ppb SIDA water Rychlik 1998 · 1 studies —

In a food matrix

1.0 ppb – 1576 ppb

Measured in a real food, where the matrix shifts detection — not a clean-water value.

Threshold Matrix Source Paper
1.0 ppb water (food: beef vegetable gravy) Literature corpus —
1.0 ppb water (food: pork vegetable gravy) Literature corpus —
3.9 ppb water (food: reference standard (water)) Literature corpus —
54.0 ppb water (food: wine) Literature corpus —
55.0 ppb water (food: smoked cooked loin (pork)) Literature corpus —
100 ppb water (food: litsea pungens fruit) Literature corpus —
550 ppb water (food: longjing green tea infusion) Literature corpus —
1042 ppb water (food: tea) Literature corpus —
1088 ppb water (food: beef) Literature corpus —
1576 ppb water (food: unknown) Literature corpus —

In air

0.054 ppb

Airborne detection — not comparable to a water threshold.

Threshold Matrix Source Paper
0.054 ppb air Nagata 2003 —

Other matrix

68.0 ppb – 82.0 ppb

Measured in a non-aqueous medium (oil, starch, cellulose).

Threshold Matrix Source Paper
68.0 ppb oil (sunflower oil) (food: cocoa beans) Literature corpus —
68.0 ppb oil (sunflower oil) (food: cocoa powder) Literature corpus —
81.5 ppb ethanol/water 40/60 (food: rum (aged)) Literature corpus —
82.0 ppb ethanol/water (food: rum) Literature corpus —

Only values we can attribute are listed. Where a compendium's licence does not permit public attribution its figures are omitted here, so every number on this page traces to a citable source.

Where you'd actually smell it

Odor Activity Value = measured concentration ÷ odor threshold (61.5 ppb, the engine's canonical value — see the 16 published values). OAV ≥ 1 = perceptible.

Food Concentration (ppb) OAV Source
beef 3800.0 61.8 ⚡ Corpus paper

Concentrations from PubMed Central Open Access papers (free literature corpus, MIT-style licensed). Copper = OAV ≥ 10 (strongly perceptible). Green = OAV ≥ 1 (perceptible).

Found in

Measured impact first, then profile share

Every ingredient known to contain 4-methylphenol. Ingredients with a measured concentration come first, ranked by odour activity; the rest follow by how large a share of that ingredient's profile this molecule is. The figure beside each is how many different compounds that ingredient has in total — not the concentration of 4-methylphenol in it. Full concentrations are in the OAV table above.

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