5-methyl-2,3-diethylpyrazine

roasted pyrazine Key food odorant

Found in 2 ingredients across the CompKitchen flavor graph.

Look up another compound — search by name, CAS number, PubChem CID, or FEMA #.

Key food odorant (intermediary)

Dunkel et al. 2014

Identified in the meta-analysis of 227 food samples as one of 57 intermediary odorants — appears in 5–25% of foods.

Source: Angew. Chem. Int. Ed. 2014, 53, 7124–7143

Properties

Odor threshold — orthonasal, in clean water: 0.090 ppb 1 published value · see all 9 with sources
CAS number: 18138-04-0

Not in FEMA GRAS publications 1-33. Of 3,367 listed flavoring substances, none match this compound name. May still be food-safe under other regulatory routes (FDA 21 CFR 172, EFSA, JECFA) — check femaflavor.org for the authoritative current list.

Published thresholds

9 measured values from the literature. Grouped by what was actually measured — a threshold smelled in clean water, tasted in the mouth, or measured in a real food are three different quantities and are not pooled.

Orthonasal, in clean water

0.090 ppb

The reference measurement — smelled in water. OAV is computed against this.

Threshold	Matrix	Source	Paper
0.090 ppb SIDA	water	Rychlik 1998 · 1 studies	—

In a food matrix

0.016 ppb

Measured in a real food, where the matrix shifts detection — not a clean-water value.

Threshold	Matrix	Source	Paper
0.016 ppb	water (food: longjing green tea infusion)	Literature corpus	—

Retronasal / in-mouth

0.050 ppb – 0.900 ppb

Tasted rather than smelled — a different sense, not comparable.

Threshold	Matrix	Source	Paper
0.050 ppb SIDA	water_retronasal	Rychlik 1998 · 1 studies	—
0.900 ppb SIDA	oil_retronasal	Rychlik 1998 · 1 studies	—

Other matrix

0.140 ppb – 1.2 ppb

Measured in a non-aqueous medium (oil, starch, cellulose).

Threshold	Matrix	Source	Paper
0.140 ppb SIDA	starch	Rychlik 1998 · 1 studies	—
0.500 ppb SIDA	oil_orthonasal	Rychlik 1998 · 1 studies	—
0.500 ppb	oil (sunflower oil) (food: cocoa beans)	Literature corpus	—
0.500 ppb	oil (sunflower oil) (food: cocoa powder)	Literature corpus	—
1.2 ppb SIDA	cellulose	Rychlik 1998 · 1 studies	—

Only values we can attribute are listed. Where a compendium's licence does not permit public attribution its figures are omitted here, so every number on this page traces to a citable source.

Found in

Measured impact first, then profile share

Every ingredient known to contain 5-methyl-2,3-diethylpyrazine. Ingredients with a measured concentration come first, ranked by odour activity; the rest follow by how large a share of that ingredient's profile this molecule is. The figure beside each is how many different compounds that ingredient has in total — not the concentration of 5-methyl-2,3-diethylpyrazine in it.

99 cmpds

Into the chemistry?

Get a molecule-level pairing breakdown each week — which ingredients share a compound, and why it matters at the table. Free, no spam.

Prefer an account? Create a free account to save pairings and unlock the full chemistry.

Try the pairing tools to see which ingredient combinations rely on 5-methyl-2,3-diethylpyrazine, or compare two ingredients side-by-side.