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l-isoleucine

other nitrogen compound

Found in 559 ingredients across the CompKitchen flavor graph.

Look up another compound — search by name, CAS number, PubChem CID, or FEMA #.

2D Lewis structure of l-isoleucine
2D Lewis Structure
Formula
C6H13NO2
Molecular weight
131.17 g/mol
PubChem CID
6306 — full record on PubChem

Properties

Odor description
odorless, bitter
Odor threshold — in a food matrix
0.120 ppb – 86.0 ppb median 1.6 ppb · 6 published values · see all 6 with sources
Volatility
low
CAS number
73-32-5
Regulatory · United States

FEMA GRAS — Generally Recognized As Safe for flavoring use

✓ Exact match
FEMA number
4675
GRAS publication
GRAS 25
FEMA primary name
L-ISOLEUCINE

Use-level matrix not extracted for this substance — check the source publication for current ppm guidance.

Source: FEMA GRAS publications 1-33.

Published thresholds

6 measured values from the literature. Grouped by what was actually measured — a threshold smelled in clean water, tasted in the mouth, or measured in a real food are three different quantities and are not pooled.

In a food matrix

0.120 ppb – 86.0 ppb

Measured in a real food, where the matrix shifts detection — not a clean-water value.

Threshold Matrix Source Paper
0.120 ppb water (food: onion) Literature corpus —
0.674 ppb water (food: unknown) Literature corpus —
1.0 ppb water (food: rice) Literature corpus —
2.1 ppb water (food: fish) Literature corpus —
19.4 ppb water (food: mushroom) Literature corpus —
86.0 ppb water (food: milk) Literature corpus —

Only values we can attribute are listed. Where a compendium's licence does not permit public attribution its figures are omitted here, so every number on this page traces to a citable source.

Found in

Measured impact first, then profile share

Every ingredient known to contain l-isoleucine. Ingredients with a measured concentration come first, ranked by odour activity; the rest follow by how large a share of that ingredient's profile this molecule is. The figure beside each is how many different compounds that ingredient has in total — not the concentration of l-isoleucine in it.

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